GKT-137831 for cell activation
Catalog number
9444-25
Name
GKT-137831 for cell activation
Size
25 mg
Price
588.00 EUR
Supplier
Details
Description
GKT-137831 is a novel pyrazolopyridinedione derivative that acts as a Nox4 and Nox1 inhibitor ((Ki 100–150 nM). GKT-137831 attenuates hypoxia-induced pulmonary vascular cell proliferation. Also a potent inhibitor of fibrosis and hepatocyte apoptosis.
Peptide sequence
N/A
CAS number
1218942-37-0
Molecular weight
394.85
Category
Biochemicals
Other name
2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione
Molecular formula
C21H20ClN4O2
Physical appearance
Light yellow to yellow solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
