SP-2509 for cell activation
Catalog number
9446-5
Name
SP-2509 for cell activation
Size
5 mg
Price
153.00 EUR
Supplier
Details
Description
SP-2509 is a reversible inhibitor of Lysine-specific demethylase (LSD1) (IC₅₀ = 13 nM). It has no effect on monoamine oxidases A and B. SP2509 attenuates the binding of LSD1 to CoREST, allowing increased methylation of H3K4 and driving increased expression of p21, p27, and CCAAT/enhancer binding protein α in cultured acute myeloid leukemia (AML) cells.
Peptide sequence
N/A
CAS number
1423715-09-6
Molecular weight
437.9
Category
Biochemicals
Other name
3-(4-morpholinylsulfonyl)-benzoic acid (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide
Molecular formula
C₁₉H₂₀ClN₃O₅S
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~25 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
