GW-6471 for cell activation
Catalog number
9453-5
Name
GW-6471 for cell activation
Size
5 mg
Price
371.00 EUR
Supplier
Details
Description
GW-6471 is a potent PPARα antagonist (IC₅₀ = 240 nM). It drives the displacement of coactivators from PPARα and promotes the recruitment of co-repressor proteins like nuclear co-repressor. GW-6471 significantly prevents cardiomyocyte differentiation and results in the reduced expression of cardiac sarcomeric proteins and specific genes in a time-dependent manner.
Peptide sequence
N/A
CAS number
880635-03-0
Molecular weight
619.67
Category
Biochemicals
Other name
N-((2S)-2-(((1Z)-1-Methyl-3-oxo-3-(4-(trifluoromethyl)phenyl)prop-1-enyl)amino)-3-(4-(2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy)phenyl)propyl)propanamide
Molecular formula
C₃₅H₃₆F₃N₃O₄
Physical appearance
Cream-colored solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO (~40 mg/ml) or EtOH (~10 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
