Amuvatinib for cell activation
Catalog number
9458-5
Name
Amuvatinib for cell activation
Size
5 mg
Price
186.00 EUR
Supplier
Details
Description
Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC₅₀ values of 10 nM, 40 nM and 81 nM, respectively. It also disrupts DNA repair likely through suppression of Homologous Recombination protein Rad51.
Peptide sequence
N/A
CAS number
850879-09-3
Molecular weight
447.51
Category
Biochemicals
Other name
N-(Benzo[d][1,3]dioxol-5-ylmethyl)-4-(benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide; MP-470; HPK56
Molecular formula
C₂₃H₂₁N₅O₃S
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>30 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
