PF-05212384 for cell activation
Catalog number
9461-50
Name
PF-05212384 for cell activation
Size
50 mg
Price
757.00 EUR
Supplier
Details
Description
PF-05212384 is a potent, selective and ATP-competitive dual inhibitor of PI 3-kinase/mTOR (IC₅₀ values are 0.4, 1.6 and 5.4 nM for PI 3-Kα, mTOR and PI 3-Kγ respectively). Exhibits selectivity over 234 other protein kinases (IC₅₀ >10 μM). Potently inhibits tumor cell growth in 37 different tumor cell lines (IC₅₀ < 100 nM).
Peptide sequence
N/A
CAS number
1197160-78-3
Molecular weight
615.73
Category
Biochemicals
Other name
N-[4-[[4-(Dimethylamino)-1-piperidinyl]carbonyl]phenyl]-N'-[4-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)phenyl]urea; Gedatolisib; PKI-587
Molecular formula
C₃₂H₄₁N₉O₄
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~ 3 mg/ml with slight warming)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
