GSK-2606414 for cell activation
Catalog number
9467-25
Name
GSK-2606414 for cell activation
Size
25 mg
Price
632.00 EUR
Supplier
Details
Description
GSK-2606414 is a potent and selective inhibitor of protein kinase R-like ER kinase (PERK) with IC₅₀ value of 0.4 nM. Displays >1000-fold selectivity for PERK over HR1 and PKR. GSK-2606414 inhibits PERK activation in cells and inhibits the growth of a human tumor xenograft in mice.
Peptide sequence
N/A
CAS number
1337531-36-8
Molecular weight
451.44
Category
Biochemicals
Other name
1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone
Molecular formula
C₂₄H₂₀F₃N₅O
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>30 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
