LY-2157299 for cell activation
Catalog number
9475-5
Name
LY-2157299 for cell activation
Size
5 mg
Price
153.00 EUR
Supplier
Details
Description
LY-2157299 is a potent and selective TGFβ receptor I (TβRI) inhibitor (IC₅₀ = 56 nM). LY-2157299 abolishes the TGFβ induced Smad2 phosphorylation in HUVEC cells. It also shows dose dependent potentiation of VEGF or bFGF induced cell proliferation in HUVEC.
Peptide sequence
N/A
CAS number
700874-72-2
Molecular weight
369.42
Category
Biochemicals
Other name
4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide; Galunisertib
Molecular formula
C₂₂H₁₉N₅O
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>50 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
