MDV-3100 for cell activation
Catalog number
9479-10
Name
MDV-3100 for cell activation
Size
10 mg
Price
208.00 EUR
Supplier
Details
Description
MDV-3100 (Enzalutamide) is an androgen-receptor (AR) antagonist (IC₅₀ = 36 nM). Prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.
Peptide sequence
N/A
CAS number
915087-33-1
Molecular weight
464.43
Category
Biochemicals
Other name
4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide; Enzalutamide
Molecular formula
C₂₁H₁₆F₄N₄O₂S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~25 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
