PD-0332991 isethionate for cell activation
Catalog number
9480-25
Name
PD-0332991 isethionate for cell activation
Size
25 mg
Price
545.00 EUR
Supplier
Details
Description
PD0332991 is a highly specific inhibitor of Cdk4 (IC₅₀ = 11 nM) and Cdk6 (IC₅₀ = 16 nM). Displays selectivity for Cdk4/6 over a panel of 34 additional protein kinases (IC₅₀ values are > 10 μM).
Peptide sequence
N/A
CAS number
827022-33-3
Molecular weight
573.66
Category
Biochemicals
Other name
6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one isethionate salt; Palbociclib
Molecular formula
C₂₄H₂₉N₇O₂.C₂H₆O₄S
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
Water (~55 mg/ml) or DMSO (~ 6 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
