Zosuquidar trihydrochloride for cell activation
Catalog number
9488-5
Name
Zosuquidar trihydrochloride for cell activation
Size
5 mg
Price
208.00 EUR
Supplier
Details
Description
Zosuquidar is a potent P-glycoprotein (P-gp) inhibitor (Kd = 79 nM). Zosuquidar binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated multidrug resistance (MDR). Restores doxorubicin (Cat. No. 1527) sensitivity in P-gp-expressing multidrug (MDR) resistant cancer cell lines.
Peptide sequence
N/A
CAS number
167465-36-3
Molecular weight
636.99
Category
Biochemicals
Other name
(αR)-4-[(1aα,6α,10bα)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-1-piperazineethanol trihydrochloride; LY335979
Molecular formula
C₃₂H₃₁FN₃O.3HCl
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>25 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
