Eltrombopag for cell activation

Catalog number

9489-25

Size

25 mg

Price

458.00 EUR

Supplier

Biovision

Order

Details

Description

Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily.

Peptide sequence

N/A

CAS number

496775-61-2

Molecular weight

442.47

Category

Biochemicals

Other name

3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; SB-497115; SB-497115-GR

Molecular formula

C₂₅H₂₂N₄O₄

Physical appearance

Crystalline solid

Supplied with

N/A

Is this a salt?

N/A

Is it cell-permeable?

Yes

Purification

≥98% by HPLC