Avasimibe for cell activation
Catalog number
9506-5
Name
Avasimibe for cell activation
Size
5 mg
Price
142.00 EUR
Supplier
Details
Description
Avasimibe is an orally bioavailable inhibitor of the acyl coenzyme A: cholesterol acyltransferase (ACAT) (IC₅₀ = 60 nM). Avasimibe also inhibits major drug metabolizing enzymes such as CYP2C9 (IC₅₀ = 2.9 µM ), CYP1A2 (IC₅₀ = 13.9 µM), and CYP2C19 (IC₅₀ = 26.5 µM).
Peptide sequence
N/A
CAS number
166518-60-1
Molecular weight
501.72
Category
Biochemicals
Other name
[2,6-di(propan-2-yl)phenyl] N-[2-[2,4,6-tri(propan-2-yl)phenyl]acetyl]sulfamate; CI-1011; PD 148515
Molecular formula
C₂₉H₄₃NO₄S
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>35 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
