DMH-1 for cell activation
Catalog number
9542-5
Name
DMH-1 for cell activation
Size
5 mg
Price
186.00 EUR
Supplier
Details
Description
DMH-1 is an analog of Dorsomorphin (Cat. No. 1686) that acts as a highly selective Bone morphogenetic protein (BMP) inhibitor. DMH-1 exclusively targets the BMP but not the VEGF pathway. Blocks BMP4-induced phosphorylation of Smads 1, 5 and 8 in HEK293 cells. Promotes neurogenesis in human induced pluripotent stem cells (iPSCs) when used in combination with SB-431542 (Cat. No. 1674).
Peptide sequence
N/A
CAS number
1206711-16-1
Molecular weight
380.44
Category
Biochemicals
Other name
4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Molecular formula
C₂₄H₂₀N₄O
Physical appearance
Pale orange solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
