STF-118804 for cell activation
Catalog number
9552-5
Name
STF-118804 for cell activation
Size
5 mg
Price
186.00 EUR
Supplier
Details
Description
STF-118804 is a potent and highly specific inhibitor of Nampt (nicotinamide phosphoribosyl transferase) (IC₅₀s = 3-6 nM) that prevents NAD⁺ synthesis from nicotinamide. It inhibits the viability of multiple B-cell acute lymphoblastic leukemia (B-ALL) cell lines with nanomolar potency and induces apoptosis in MV411 cells. It improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia, and targets leukemia stem cells.
Peptide sequence
N/A
CAS number
894187-61-2
Molecular weight
461.53
Category
Biochemicals
Other name
4-(5-methyl-4-(tosylmethyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide
Molecular formula
C₂₅H₂₃N₃O₄S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>30 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
