Conduritol B Epoxide for cell activation

Conduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid β-glucosidase, glucosylceramidase, GBA, or GBA1 (IC₅₀ = 9 μM). Inhibition of this lysosomal glucosidase results in the accumulation of glucocerebroside without affecting cell viability, lysosomal enzyme release, or the activity of intracellular enzymes. It also does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase.

N/A

6090-95-5

162.14

Biochemicals

D,L-1,2-Anhydro-myo-inositol; CBE

C₆H₁₀O₅

White to off-white solid

N/A

No

Yes

≥98%

DMSO ~25 mg/ml)

-20°C

gel pack

36 months

Protect from air and moisture

cell

For cells, cell lines and tissues in culture till half confluency.