Conduritol B Epoxide for cell activation

Catalog number
9574-5
Name
Conduritol B Epoxide for cell activation
Size
5 mg
Price
175.00 EUR
Supplier

Details

Description
Conduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid β-glucosidase, glucosylceramidase, GBA, or GBA1 (IC₅₀ = 9 μM). Inhibition of this lysosomal glucosidase results in the accumulation of glucocerebroside without affecting cell viability, lysosomal enzyme release, or the activity of intracellular enzymes. It also does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase.
Peptide sequence
N/A
CAS number
6090-95-5
Molecular weight
162.14
Category
Biochemicals
Other name
D,L-1,2-Anhydro-myo-inositol; CBE
Molecular formula
C₆H₁₀O₅
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO ~25 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.