CCT244747 for cell activation
Catalog number
9575-5
Name
CCT244747 for cell activation
Size
5 mg
Price
240.00 EUR
Supplier
Details
Description
CCT244747 is a potent, selective and ATP-competitive CHK1 inhibitor. CCT244747 inhibits cellular CHK1 activity (IC₅₀ = 29-170 nmol/L), significantly enhances the cytotoxicity of several anticancer drugs, and abrogates drug-induced S and G(2) arrest in multiple tumor cell lines.
Peptide sequence
N/A
CAS number
1404095-34-6
Molecular weight
408.46
Category
Biochemicals
Other name
(R)-3-((1-(dimethylamino)propan-2-yl)oxy)-5-((4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl)amino)pyrazine-2-carbonitrile
Molecular formula
C₂₀H₂₄N₈O₂
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO ~5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
