EHop-016 for cell activation
Catalog number
9595-5
Name
EHop-016 for cell activation
Size
5 mg
Price
153.00 EUR
Supplier
Details
Description
EHop-016 is an analog of NSC-23766 (Cat. No. 1941) that acts as a potent inhibitor of Rac GTPase (IC₅₀ = 1.1 µM for Rac1). The IC₅₀ of 1.1 μM for Rac inhibition by EHop-016 is ∼100-fold lower than for NSC-23766. EHop-016 is specific for Rac1 and Rac3 at concentrations of ≤5 μM. At higher concentrations, EHop-016 inhibits the close homolog Cdc42.
Peptide sequence
N/A
CAS number
1380432-32-5
Molecular weight
430.55
Category
Biochemicals
Other name
4-N-(9-ethylcarbazol-3-yl)-2-N-(3-morpholin-4-ylpropyl)pyrimidine-2,4-diamine
Molecular formula
C₂₅H₃₀N₆O
Physical appearance
Pale yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
