BMS-299897 for cell activation
Catalog number
9606-5
Name
BMS-299897 for cell activation
Size
5 mg
Price
208.00 EUR
Supplier
Details
Description
BMS-299897 is a potent, brain-permeant γ-secretase inhibitor (IC₅₀ = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC₅₀ values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo. Displays no Notch toxicity.
Peptide sequence
N/A
CAS number
290315-45-6
Molecular weight
511.94
Category
Biochemicals
Other name
(R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoic acid
Molecular formula
C₂₄H₂₁ClF₃NO₄S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>40 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
