Iron Chelator, Dp44MT for cell activation

Catalog number
9634-5
Name
Iron Chelator, Dp44MT for cell activation
Size
5 mg
Price
132.00 EUR
Supplier

Details

Description
Dp44MT is a cell-permeable iron chelator. This di-2-pyridyl thiosemicarbazone (DpT) based tridentate ligand displays potent and selective antiproliferative properties in neoplastic cells and minimally affects normal cells. Dp44mT prevents aggressive growth of M109 lung carcinoma in mice and has been shown to mobilize cellular iron effectively, and generate ROS leading to apoptosis.
Peptide sequence
N/A
CAS number
152095-12-0
Molecular weight
285.37
Category
Biochemicals
Other name
2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide, Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone
Molecular formula
C₁₄H₁₅N₅S
Physical appearance
Yellow to orange solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO (>5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.