KC7F2 for cell activation
Catalog number
9641-10
Name
KC7F2 for cell activation
Size
10 mg
Price
153.00 EUR
Supplier
Details
Description
KC7F2 is a small molecule HIF-1 pathway inhibitor that inhibits HIF-1α protein translation, but not transcription. It inhibits hypoxia-induced expression of several HIF target genes, such as carbonic anhydrase IX, matrix metalloproteinase 2, enolase 1, and endothelin 1. KC7F2 is cytotoxic to a variety of cancer cell lines with an IC₅₀ value of 15-25 µM.
Peptide sequence
N/A
CAS number
927822-86-4
Molecular weight
570.38
Category
Biochemicals
Other name
N,N'-(dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonamide
Molecular formula
C₁₆H₁₆Cl₄N₂O₄S₄
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>50 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
