NQDI-1 for cell activation
Catalog number
9645-50
Name
NQDI-1 for cell activation
Size
50 mg
Price
588.00 EUR
Supplier
Details
Description
NQDI-1 is a specific inhibitor of apoptosis signal-regulating kinase 1 (ASK1) (IC₅₀ = 3 μM; Ki = 500 nM) that demonstrates potent selectivity against various serine/threonine and tyrosine protein kinases. It has been used to promote survival of induced pluripotent stem cell populations and to protect neurons from reactive oxygen species-induced apoptosis in a model of ischemia.
Peptide sequence
N/A
CAS number
175026-96-7
Molecular weight
319.31
Category
Biochemicals
Other name
2,7-dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid, ethyl ester
Molecular formula
C₁₉H₁₃NO₄
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
