ODM-201 for cell activation
Catalog number
9668-25
Name
ODM-201 for cell activation
Size
25 mg
Price
675.00 EUR
Supplier
Details
Description
ODM-201 is a new-generation, potent and selective androgen receptor (AR) antagonist (Ki = 11 nM). In AR overexpressing HS-HEK293 cells, ODM-201 inhibits the androgen-induced nuclear translocation of overexpressed AR. In the VCaP cell line with endogenous AR gene amplification and AR overexpression, ODM-201 inhibits androgen-induced cell proliferation with IC₅₀ value of 230 nM.
Peptide sequence
N/A
CAS number
1297538-32-9
Molecular weight
389.85
Category
Biochemicals
Other name
N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
Molecular formula
C₁₉H₁₉ClN₆O₂
Physical appearance
Whte to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
