PS-1145 for cell activation

Catalog number
9671-5
Name
PS-1145 for cell activation
Size
5 mg
Price
208.00 EUR
Supplier

Details

Description
PS-1145 is a potent and selective IκB kinase (IKK) inhibitor (IC₅₀ = 100 nM). Has no effect on PKA, PKC and CKII activity. PS-1145 efficiently inhibits both basal and induced NF-κB activity in PC cells. Enhances TNF-α-induced apoptosis in a multiple myeloma cell line.
Peptide sequence
N/A
CAS number
431898-65-6 
Molecular weight
322.75
Category
Biochemicals
Other name
N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)nicotinamide
Molecular formula
C₁₇H₁₁ClN₄O
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.