Crenolanib for cell activation
Catalog number
9679-5
Name
Crenolanib for cell activation
Size
5 mg
Price
142.00 EUR
Supplier
Details
Description
Crenolanib is a highly selective and potent FLT3 tyrosine kinase inhibitor (TKI) with activity against the internal tandem duplication (FLT3/ITD) mutants and the FLT3/D835 point mutants. Also displays inhibitory activity against PDGFRα/β with Kd of 2.1 nM/3.2 nM in CHO cells.
Peptide sequence
N/A
CAS number
670220-88-9
Molecular weight
443.54
Category
Biochemicals
Other name
1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine; CP-868596; ARO 002
Molecular formula
C₂₆H₂₉N₅O₂
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>40 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
