ACE2 Inhibitor, DX600 for cell activation

DX600 is a potent ACE2 (Angiotensin-Converting Enzyme 2) inhibitor (Ki = 2.8 nM).

Ac - Gly - Asp - Tyr - Ser - His - Cys - Ser - Pro - Leu - Arg - Tyr - Tyr - Pro - Trp - Trp - Lys - Cys - Thr - Tyr - Pro - Asp - Pro - Glu - Gly - Gly - Gly - NH2

N/A

3076.4

Biochemicals

DX600; Ac-GDYSHCSPLRYYPWWKCTYPDPEGGG-NH2

C₁₄₁H₁₈₇N₃₅O₄₀S₂

Lyophilized solid

N/A

No

Yes

≥95% by HPLC

H₂O (~2 mg/ml)

-20°C

gel pack

36 months

Protect from moisture

cell

For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.