7BIO for cell activation

Catalog number

9690-5

Size

5 mg

Price

186.00 EUR

Supplier

Biovision

Order

Details

Description

7BIO is a caspase- independent nonapoptotic cell death inducer. Also acts as an ATP-competitive FLT3 inhibitor and DYRK1A and DYRK 2 (Dual-specificity tyrosine phosphorylation-regulated kinase) inhibitor. In addition, 7BIO is a necrosis inducer and inflammasome activator. Also a potent inhibitor of Aurora kinase B and C.

Peptide sequence

N/A

CAS number

916440-85-2

Molecular weight

356.2

Category

Biochemicals

Other name

7-Bromoindirubin-3'-oxime

Molecular formula

C₁₆H₁₀BrN₃O₂

Physical appearance

Dark red solid

Supplied with

N/A

Is this a salt?

Is it cell-permeable?

Yes

Purification

≥98% by NMR

Reconstitute instructions

DMSO

Storage condition

-20°C

Shipping condition

gel pack

Maximum time for storage

36 months

Storage instructions

Protect from air and light

Tissue

cell

Additional description

For cells, cell lines and tissues in culture till half confluency.