Ro 48-8071 fumarate for cell activation
Catalog number
B1042-10
Name
Ro 48-8071 fumarate for cell activation
Size
10 mg
Price
175.00 EUR
Supplier
Details
Description
Ro 48-8071 is a selective 2,3-Oxidosqualene:lanosterol cyclase (OSC) inhibitor (IC₅₀ = 6.5 nM); blocks cholesterol synthesis in HepG2 cells. Ro 48-8071 exerts strong anti-angiogenic activity by impairing endothelial cell adhesion and migration, and by blocking vessel formation in angiogenesis assays.
Peptide sequence
N/A
CAS number
189197-69-1
Molecular weight
564.44
Category
Biochemicals
Other name
(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone fumarate
Molecular formula
C₂₃H₂₇BrFNO₂.C₄H₄O₄
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>50 mg/ml) or H₂O (>5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
