CAY10683 for cell activation
Catalog number
B1051-25
Name
CAY10683 for cell activation
Size
25 mg
Price
458.00 EUR
Supplier
Details
Description
CAY10683 is a potent histone deacetylase (HDAC) inhibitor isolated from the cyanobacterium Symploca. It inhibits HDAC2 and HDAC6 with IC₅₀ values of 0.119 and 434 nM, respectively. Inhibits HDAC4 only at higher concentrations (IC₅₀ = >1,000 nM). CAY10683 inhibits the growth of HCT-116 colon cancer cells and HuT-78 cutaneous T cell lymphoma cells (GI₅₀ = 29.4 and 1.4 μM, respectively) more effectively than human dermal fibroblasts (GI₅₀ = >100 μM.
Peptide sequence
N/A
CAS number
1477949-42-0
Molecular weight
278.35
Category
Biochemicals
Other name
EthylN-[4-oxo-4-(2-phenylethylamino)butyl]carbamate; Santacruzamate A
Molecular formula
C₁₅H₂₂N₂O₃
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~25 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
