BIBS39 for cell activation
Catalog number
B1071-25
Name
BIBS39 for cell activation
Size
25 mg
Price
545.00 EUR
Supplier
Details
Description
BIBS-39 is a novel, nonpeptide angiotensin II receptor antagonist that displays antihypertensive activity. In contrast to the angiotensin II receptor subtype 1 (AT1) selective drug DuP 753, BIBS-39 also displays affinity for the angiotensin II receptor subtype 2. BIBS 39 displaces [125I] AII from its specific binding sites with a K(i) value of 29 +/- 7 nM for the AII subtype I (AT1) receptor and a K(i) value of 480 +/- 110 nM for the AII subtype 2 (AT2) receptor.
Peptide sequence
N/A
CAS number
133085-33-3
Molecular weight
524.66
Category
BioChemicals
Other name
4'-((2-Butyl-6-(((cyclohexylamino)carbonyl)amino)-1H-benzimidazo-1-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid
Molecular formula
C₃₂H₃₆N₄O₃
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
