JNJ-42041935 for cell activation
Catalog number
B1072-5
Name
JNJ-42041935 for cell activation
Size
5 mg
Price
175.00 EUR
Supplier
Details
Description
JNJ-42041935 is a HIF-PHD (Hypoxia-inducible factor- prolyl hydroxylase) inhibitor. JNJ-42041935 is a selective, 2-OG (2-oxoglutarate) competitive, and reversible inhibitor of PHD enzymes (pKis = 7.91, 7.29, and 7.65 for PHD1, 2, and 3, respectively). It is >100-fold selective for PHD compared to the related FIH (factor-inhibiting HIF) and a panel of various other enzymes.
Peptide sequence
N/A
CAS number
1193383-09-3
Molecular weight
346.65
Category
BioChemicals
Other name
1-[6-chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1H-pyrazole-4-carboxylic acid
Molecular formula
C₁₂H₆ClF₃N₄O₃
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
no
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>30 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
