K858 for cell activation
Catalog number
B1073-50
Name
K858 for cell activation
Size
50 mg
Price
632.00 EUR
Supplier
Details
Description
K858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor (IC₅₀ = 1.3 µM) and an antitumor agent. Induces cell death in cancer cells, blocks centrosome separation, activates the spindle checkpoint, and induces mitotic arrest in cells accompanied by the formation of monopolar spindles.
Peptide sequence
N/A
CAS number
72926-24-0
Molecular weight
277.34
Category
BioChemicals
Other name
N-(4-acetyl-5-methyl-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl)acetamide
Molecular formula
C₁₃H₁₅N₃O₂S
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
