Mirin for cell activation
Catalog number
B1075-10
Name
Mirin for cell activation
Size
10 mg
Price
197.00 EUR
Supplier
Details
Description
Mirin is a small-molecule inhibitor of MRN (Mre11, Rad50, and Nbs1) complex. Mirin blocks the 3' and 5' exonuclease activity associated with Mre11. Prevents ATM activation in response to double strand breaks (IC₅₀ = 12 μM) and induces G2 cell cycle arrest.
Peptide sequence
N/A
CAS number
1198097-97-0
Molecular weight
220.25
Category
Biochemicals
Other name
Z-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one
Molecular formula
C₁₀H₈N₂O₂S
Physical appearance
Pale yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
