SU 16f for cell activation
Catalog number
B1081-25
Name
SU 16f for cell activation
Size
25 mg
Price
632.00 EUR
Supplier
Details
Description
SU 16f is a potent, cell-permeable and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC₅₀ = 10 nM). It displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC₅₀ = 0.11 μM).
Peptide sequence
N/A
CAS number
251356-45-3
Molecular weight
386.44
Category
Biochemicals
Other name
5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid
Molecular formula
C₂₄H₂₂N₂O₃
Physical appearance
Red brown solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>35 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
