(S)-H-1152 dihydrochloride for cell activation

Catalog number
B1106-5
Name
(S)-H-1152 dihydrochloride for cell activation
Size
5 mg
Price
545.00 EUR
Supplier

Details

Description
H-1152 dihydrochloride is a potent, cell permeable, specific, ATP-competitive inhibitor of Rho-kinase (ROCK) (Ki = 1.6 nM).  H-1152 poorly inhibits PKA, PKC, and myosin light chain kinase (Ki = 0.63, 9.27, and 10.1 μM, respectively).
Peptide sequence
N/A
CAS number
451462-58-1
Molecular weight
392.34
Category
Biochemicals
Other name
(S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride
Molecular formula
C₁₆H₂₁N₃O₂S.2HCl
Physical appearance
White Solid
Supplied with
N/A
Is this a salt?
Yes
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>15 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.