NU-7441 for cell activation
Catalog number
B1117-25
Name
NU-7441 for cell activation
Size
25 mg
Price
545.00 EUR
Supplier
Details
Description
NU-7441 is a potent and selective DNA-PK inhibitor (IC₅₀ = 14 nM). Displays selectivity for DNA-PK over a range of kinases including mTOR, PI 3-K, ATM and ATR. Also enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency, and attenuates nonhomologous end-joining (NHEJ).
Peptide sequence
N/A
CAS number
503468-95-9
Molecular weight
413.49
Category
Biochemicals
Other name
8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one; KU-57788
Molecular formula
C₂₅H₁₉NO₃S
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~ 2 mg/ml with gentle warming)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
