IMR-1 for cell activation
Catalog number
B1131-25
Name
IMR-1 for cell activation
Size
25 mg
Price
567.00 EUR
Supplier
Details
Description
IMR-1 (Inhibitor of Mastermind Recruitment-1), is a small molecule inhibitor that disrupts the recruitment of Mastermind-like 1 to the Notch transcriptional activation complex on chromatin, thereby attenuating Notch target gene transcription. Additionally, IMR-1 inhibits the growth of Notch-dependent cell lines and significantly abrogates the growth of patient-derived tumor xenografts.
Peptide sequence
N/A
CAS number
310456-65-6
Molecular weight
353.41
Category
Biochemicals
Other name
(E)-Ethyl 2-(2-methoxy-4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenoxy)acetate; Inhibitor of Mastermind Recruitment-1
Molecular formula
C₁₅H₁₅NOS₂
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
