GW-441756 for cell activation
Catalog number
B1147-25
Name
GW-441756 for cell activation
Size
25 mg
Price
632.00 EUR
Supplier
Details
Description
GW-441756 is potent and specific inhibitor of Trk A (tropomyosin-related kinase A) tyrosine kinase (IC₅₀ = 2 nM). This inhibition of TrkA reduces cell proliferation and enhances the effects of chemotherapeutic agents in sarcoma. GW-441756 displays >100-fold selectivity over a range of other kinases.
Peptide sequence
N/A
CAS number
504433-23-2
Molecular weight
275.31
Category
Biochemicals
Other name
1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one
Molecular formula
C₁₇H₁₃N₃O
Physical appearance
Red Solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~4 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
