PF-04418948 for cell activation
Catalog number
B1168-25
Name
PF-04418948 for cell activation
Size
25 mg
Price
458.00 EUR
Supplier
Details
Description
PF-04418948 is a potent EP2 receptor antagonist with an IC₅₀ of 16 nM for human EP2 receptors. It also displays greater selectivity for EP2 receptors over EP1, 3, 4, DPI and CRTH2 receptors. It inhibits PGE2 induced increase in intracellular cAMP. In vivo activity includes reversing the PGE2 invoked relaxation of mouse trachea.
Peptide sequence
N/A
CAS number
1078166-57-0
Molecular weight
409.41
Category
Biochemicals
Other name
1-(4-fluorobenzoyl)-3-[(6-methoxynaphthalen-2-yl)oxymethyl]azetidine-3-carboxylic acid
Molecular formula
C₂₃H₂₀FNO₅
Physical appearance
White Solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>40 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
