Cytochalasin D for cell activation

Cytochalasin D is a cell-permeable fungal toxin that acts as a potent inhibitor of actin polymerization; disrupts actin microfilaments; activates the p53-dependent pathways. It is about 10-fold more effective than Cytochalasin B and does not inhibit monosaccharide transport across cell membranes. Inactivates low conductance K⁺ channels. Modulates CD4 cross-linking in T-lymphocytes and increases intracellular Ca2+levels. Exhibits antitumor activity. Induces apoptosis.

N/A

22144-77-0

507.6

Biochemicals

Zygosporin A

C₃₀H₃₇NO₆

White to off-white solid

N/A

N/A

Yes

≥95%

DMSO (~25 mg/ml)

-20°C

gel pack

36 months

Protect from air and light

cell

For cells, cell lines and tissues in culture till half confluency.