TMP-153 for cell activation
Catalog number
B1181-10
Name
TMP-153 for cell activation
Size
10 mg
Price
186.00 EUR
Supplier
Details
Description
TMP-153 is a selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) with IC₅₀ of 5 to 10 nM. It has potency to inhibit cholesterol esterification and reduces its influx into the plasma of rats and hamsters. TMP-153 is shown toxicity to prion infected neuronal (ScGT1) cells. It might have potential to increase caspase-3 activity and prostaglandin E2 production in ScGT1 Cells.
Peptide sequence
N/A
CAS number
128831-46-9
Molecular weight
437.88
Category
Biochemicals
Other name
N-[4-(2-chlorophenyl)-6,7-dimethyl-3-quinolinyl]-N'-(2,4-difluorophenyl)-urea
Molecular formula
C₂₄H₁₈ClF₂N₃O
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
DMSO (~25 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
