EW-7197 for cell activation
Catalog number
B1191-1
Name
EW-7197 for cell activation
Size
1 mg
Price
153.00 EUR
Supplier
Details
Description
EW-7197 is a potent ALK5 (TGF-β Type I receptor) inhibitor that displays anti metastatic activity in vivo. In vivo mice experiments show EW-7197 repeals TGF- β1 induced tumor cell migration and invasion inhibiting breast cancer metastasis to the lung. It prolongs the life span of BALB/c4T1 mice by inhibiting metastasis and enhancing the activity of cytotoxic T lymphocytes (CTLs) in 4T1 orthotropic grafted mice.
Peptide sequence
N/A
CAS number
1352608-82-2
Molecular weight
399.42
Category
Biochemicals
Other name
N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline
Molecular formula
C₂₂H₁₈FN₇
Physical appearance
White Solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>75 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
