GSK2256098 for cell activation

Catalog number
B1224-25
Name
GSK2256098 for cell activation
Size
25 mg
Price
675.00 EUR
Supplier

Details

Description
GSK2256098 (GTPL7939) is a focal adhesion kinase-1 (FAK-1) inhibitor with potential antineoplastic and antiangiogenic activity. FAK is normally activated by integrin binding to extra cellular matrix and might be upregulated and activated in various tumor types. This inhibition of FAK-1 kinase prevents downstream signal transduction pathways mediated by integrin activation including ERK, JNK/MAPK and PI3/Akt thus inhibiting tumor cell migration, proliferation and survival.
Peptide sequence
N/A
CAS number
1224887-10-8 
Molecular weight
414.89
Category
Biochemicals
Other name
2-((5-chloro-2-((1-isopropyl-3-methyl-1H-pyrazol-5-yl)amino)pyridin-4-yl)amino)-N-methoxybenzamide
Molecular formula
C₂₀H₂₃ClN₆O₂ 
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.