Lamotrigine for cell activation
Catalog number
B1234-10
Name
Lamotrigine for cell activation
Size
10 mg
Price
121.00 EUR
Supplier
Details
Description
Lamotrigine is an inhibitor of voltage-gated sodium channels (Nav), blocking human Nav1.2, Nav1.5, and Nav1.8 with IC₅₀ values of 10, 62, and 96 μM, respectively. Also blocks heterologously expressed and native α4β2 nAChRs with a similar affinity to Na+ channels. Lamotrigine acts as an anticonvulsant and has applications in many diseases that feature seizures, including epilepsy and autism spectrum disorder.
Peptide sequence
N/A
CAS number
84057-84-1
Molecular weight
256.09
Category
Biochemicals
Other name
6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine
Molecular formula
C₉H₇Cl₂N₅
Physical appearance
White solid
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>25 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
