Fostriecin sodium for cell activation
Catalog number
B1241-10
Name
Fostriecin sodium for cell activation
Size
10 µg
Price
208.00 EUR
Supplier
Details
Description
Fostriecin is a potent inhibitor of the serine/threonine protein phosphatases PP2A and PP4 with IC₅₀ value of 3.2 and 3 nM, respectively. It also displays weak inhibition of topoisomerase II having IC₅₀ of 40 μM and PP1 with IC₅₀ of 131 μM. Fostriecin has antitumor activity against a wide spectrum of tumor cells in vitro and excellent activity against P388 and L1210 leukemias in vivo.
Peptide sequence
N/A
CAS number
87860-39-7
Molecular weight
452.37
Category
Biochemicals
Other name
(6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt
Molecular formula
C₁₉H₂₆O₉PNa
Physical appearance
Coloreless solid
Supplied with
N/A
Is this a salt?
Yes
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
Water(>30 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
