Caspase Family Inhibitor Set IV for cell activation

Catalog number
K220-12-25
Name
Caspase Family Inhibitor Set IV for cell activation
Size
12x25 µl
Price
588.00 EUR
Supplier

Details

Description
A convenient set containing twelve ready-to-use capase family inhibitors. The set contains 25 µl (2 mM in DMSO) each of the following five inhibitors: Caspase-1 Inhibitor, Z-YVAD(OMe)-FMK; Caspase-2 Inhibitor, Z-VD(OMe)-VAD(OMe)-FMK; Caspase-3 Inhibitor, Z-D(OMe)-E(OMe)-VD(OMe)-FMK; Caspase-4 Inhibitor, Z-LE(OMe)VD(OMe)-FMK; Caspase-5 Inhibitor, Z-WE(OMe)HD(OMe)-FMK; Caspase-6 Inhibitor, Z-VE(OMe)ID(OMe)-FMK; Caspase-8 Inhibitor, Z-IE(OMe)TD(OMe)-FMK ; Caspase-9 Inhibitor, Z-LE(OMe)HD(OMe)-FMK; Caspase-10 Inhibitor, Z-AE(OMe)VD(OMe)-FMK; Caspase-13 Inhibitor, Z-LE(OMe)E(OMe)D(OMe)-FMK, pan Caspase Inhibitor, Z-VAD(OMe)-FMK and the negatuve control, Z-FA-FMK.
Peptide sequence
N/A
CAS number
N/A
Molecular weight
See under the individual product
Category
Biochemicals
Molecular formula
See under the individual product
Physical appearance
Liquid
Supplied with
2 mM (DMSO)
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
See under the individual product
Reconstitute instructions
N/A
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
12 months
Storage instructions
Protect from air, light and moisture
Tissue
cell, set
Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.