DiscoveryPak™ Stem Cell Fate Regulator Set III for cell activation
Catalog number
K854-3
Name
DiscoveryPak™ Stem Cell Fate Regulator Set III for cell activation
Size
3 Modulators
Price
425.00 EUR
Supplier
Details
Description
A convenient set of three small molecules useful for promoting the transformation of fibroblasts into stem cells. The three products are: 2 mg of PD 0325901 (Cat. No. 1643-2), 1 mg of SB-431542 (Cat. No. 1674-1), and 1 mg of Thiazovivin (Cat. No. 1681-1).
Peptide sequence
N/A
CAS number
See under the individual product
Molecular weight
See under the individual product
Category
Biochemicals
Other name
Stem Cell Fate Regulator Set III
Molecular formula
See under the individual product
Physical appearance
Lyophilized solids
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air, light and moisture
Tissue
cell, set, stem
Additional description
For cells, cell lines and tissues in culture till half confluency.
Test
Stem cell factors and stem cell growth factors will produce stem cells or be part of a transdifferentiation process to produce other cells. A cell can transdifferentiate by going back to the naive stem cell stadium or directly into the other cell, helped by the stem cell and transdifferentiationf actors. Stem cell growth factors or stem cell factors are mostly used to produce iPSCs or induced pluripotent stem cells by Jamaka or Thomson factors by using for example 5 Lenti-III-CMV viruses, expressing the Yamanaka iPSC factor set (Oct4, Sox2, Nanog and Lin28) + GFP positive control. Trans differentiation will omit the stem cell stadium but stem cell factors sill play an important role in trans differentiation strategies.
