PathwayReady™ PI3-K/Akt/mTOR Signaling Inhibitor Panel for cell activation

A convenient set consisting of eleven inhibitors useful for the study of PI3-K/Akt/mTOR pathway. The 11 inhibitors are: 1 mg of Akt Inhibitor, Isozyme-selective (Cat. No. 1708-1), 5 mg of BEZ-235 (Cat. No. 1626-5), 5 mg of LY-294002 (Cat. No. 1667-5), 1 mg of mTOR Inhibitor Ku-0063794 (Cat. No. 1779-1), 1 mg of PI-103 (Cat. No. 1728-1), 1 mg of PI3-Kγ Inhibitor, AS-605240 (Cat. No. 1780-1), 1 mg of PP242 (Cat. No. 1658-1), 1 mg of Rapamycin (Cat. No. 1568-1), 1 mg of TGX-221 (Cat. No. 1781-1), 1 mg of Triciribine (Cat. No. 1707-1), and 1 mg of Wortmannin (Cat. No. 1670-1).

N/A

See under the individual product

See under the individual product

Biochemicals

PI3-K/Akt/mTOR Signaling Inhibitor Panel, PathwayReady™

See under the individual product

Lyophilized solids

N/A

No

Yes

≥95% by HPLC

DMSO

-20°C

gel pack

24 months

Protect from air and light

cell, panel

For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.