PathwayReady™ EGFR Signaling Inhibitor Panel for cell activation

A convenient set consisting of fourteen inhibitors useful for the study of EGFR signaling pathway. The fouteen inhibitors are: 5 mg of AG 490 (Cat. No. 1570-5), 1 mg of Akt Inhibitor, Isozyme-Selective (Cat. No. 1708-1), 5 mg of Canertinib (Cat. No. 1617-5), 5 mg of Gefitinib (Cat. No. 1589-5), 25 mg of Lapatinib Ditosylate (Cat. No. 1624-25), 5 mg of LY 294002 (Cat. No. 1667-5), 5 mg of PD 98059 (Cat. No. 1666-5), 1 mg of PP2 (Cat. No. 1767-1), 1 mg of Rapamycin (Cat. No. 1568-1), 1 mg of SB 203580 (Cat. No. 1712-1), 25 mg of Sorafenib (Cat. No. 1594-25), 5 mg of SP 600125 (Cat. No. 1669-5), 5 mg of Stat3 Inhibitor, S3I-201 (Cat. No. 1775-5), and 1 mg of ZM 336372 (Cat. No. 1789-1).

N/A

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See under the individual product

Biochemicals

EGFR Signaling Inhibitor Panel, PathwayReady™

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Lyophilized solids

N/A

No

Yes

≥95% by HPLC

See under the individual product

-20°C

gel pack

24 months

Protect from air, light and moisture

cell, panel

For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.