DiscoveryPak™ Hedgehog (Hh) Signaling Pathway Inhibitors Set for cell activation
Catalog number
K868-6
Name
DiscoveryPak™ Hedgehog (Hh) Signaling Pathway Inhibitors Set for cell activation
Size
Inhibitors
Price
567.00 EUR
Supplier
Details
Description
A convenient set consisting of five Hedgehog (Hh) signaling pathway inhibitors and a negative control. The five inhibitors are: 50 µg of Cyclopamine-KAAD (Cat. No. 1910-50), 5 mg of GANT58 (Cat. No. 1812-5), 5 mg of GDC-0449 (Cat. No. 1890-5), 1 mg of Hh Signaling Pathway Antagonist (Cat. No. 1726-1), 1 mg of JK 184 (Cat. No. 1726-1). Also provided is 25 mg of Tomatidine hydrochloride (Cat. No. 1893-25) which can act as a negative control.
Peptide sequence
N/A
CAS number
See under the individual product
Molecular weight
See under the individual product
Category
Biochemicals
Other name
Hedgehog (Hh) Signaling Pathway Inhibitors Set
Molecular formula
See under the individual product
Physical appearance
Lyophilized solids
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
See under the individual product
Reconstitute instructions
See under the individual product
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell, set
Additional description
For cells, cell lines and tissues in culture till half confluency.Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
