Caspase Fluorometric Substrate Set

Catalog number
K131-7-25
Name
Caspase Fluorometric Substrate Set
Size
7 x 25 assays
Price
540.00 EUR
Supplier

Details

Kit's description
Fluorometric substrates for assaying activities of members of caspase family proteases. All substrates are provided in liquid ready-to-use form.
Highlights
• Detection method: Fluorescence (Ex/Em 400/505) • Species reactivity: Mammalian • Kit size:7X 25 assays • Applications: Detects specific Caspses involved in apoptosis within cells
Kit's benefits
• Contains ready-to-use caspase-1/-2/-3/-5/-6/-8/-9 AFC substrates
Category
Apoptosis Assay Kit
Kit's other name
none
Contents
• Caspase-1 Substrate, Ac-YVAD-AFC • Caspase-2 Substrate, Ac-VDVAD-AFC • Caspase-3 Substrate, Ac-DEVD-AFC • Caspase-5 Substrate, Ac-WEHD-AFC • Caspase-6 Substrate, Ac-VEID-AFC • Caspase-8 Substrate, Ac-IETD-AFC • Caspase-9 Substrate, Ac-LEHD-AFC
Storage condition
-20°C
Shipping condition
gel pack
Maximum time can be stored
6-12 months
Species reactivity
see datasheet
Applications
Detect early/middle stages of apoptosis; differentiate apoptosis from necrosis.
Samples tested
Cell culture
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.